Places still available!

In the modern chemical and pharmaceutical landscape, reactive chemical hazards represent one of the most significant risks to process safety and business continuity. Undetected thermal instabilities or improperly sized relief systems can lead to catastrophic runaway reactions, resulting in loss of life, environmental damage, and total asset loss. This intensive two-day workshop, led by industry experts from Kaypear in collaboration with the PSCI, provides a comprehensive roadmap for identifying, quantifying, and mitigating reactive risks.

Registration Process
If you are interested in attending this workshop, please register your interest below. Registration does not guarantee a place. Your attendance will be confirmed in due course. Please note that attendance is limited to one person per organization.

Who should attend
As this is a core technical topic, professionals with the following qualifications and job roles are requested to register:

• Process safety engineers/Chemical engineers in technology transfer, technical services, R&D, and process engineers with operations / technical back ground of more than 5 years is recommended.
• Engineers in senior management involved in technical reviews

Day 1

• 08:30-09:00: Registration, Networking, and Tea-Coffee
• 09:00-09:15: PSCI India Connect Overview
• 09:15-09:25: Context Setting / PSCI Audit Findings
• 09:25-09:30: Speaker Introduction
• 09:30-11:00: What reactive hazards are and why they matter with case studies: Examples of reactive hazard scenarios & Common types of reactive chemicals based on functional groups, chemical incompatibility, and thermal stability
• 11:00-11: 15:Tea Break/Net working
• 11:15-13:00: Testing and hazard evaluation using calorimetry (DSC, TGA, ARC, TMRad, ARSST, RC1, RC2, etc.)
  • Testing protocol and methods available
  • Limitation, advantage, and disadvantage of each type of calorimeter
  • Data interpretation of the thermal stability reports
• 13:00-14:00: Lunch/Networking
• 14:00-15:30: Development, calculation, and impact of heat of reaction, reaction rate, and TMRad with a workshop example
• 15:30-15:45: High Tea/Networking
• 15:45-17:00: Stossel’s Criticality Index, CCPS Probability vs Severity table - Sharing case studies - Optimization to safer criticality classes
• 17:00-17:30: Day 1 Summary & Q&A

Day 2

• 08:30-09:00: Registrations/Networking/Tea-Coffee
• 09:00-09:15: Recap & Quiz
• 09:15-11:15: Introduction to DIERS methodology and direct scale up
  • Test protocol for vent sizing using a workshop problem
  • Emergency Relief System (ERS) training for vent sizing using direct scale up
  • Scale up of high phi factor vs direct scale up
• 11:15-11:30: Tea Break/Networking
• 11:30-13:00: Credibility of external fire induced runaway reaction - Sizing for external fire scenario
• 13:00-14:00: Lunch/Networking
• 14:00-15:45: How to control reactive hazards, including:
  • Mode of operation depending on the reaction rate (Batch, Semi-Batch, Continuous)
  • Understanding the effect of temperature of no return (TNR)
  • Likelihood scale based on TMRad
  • Quench calculations and reaction termination chemicals
  • Vent sizing using direct scale up
  • Introduction of Modern DRIERS tools
• 15:45-16:00: High Tea/Networking
• 16:00-16:30: SRV/RD testing + frequency
  Type testing - Flow verification - Field observations + common issues
• 16:30-17:00: Workshop Summary & Q&A

Speakers

Mr. Rahul Raman
Rahul Raman is Principal Engineer and Subject Matter Expert at Kaypear with over 19 years of global expertise in process safety management (PSM) across the United States, Mexico, China, South Korea, and India. A Chartered Chemical Engineer with a Master's degree from Carnegie Mellon University and a B.Tech in Chemical Engineering from Anna University, he specializes in emergency relief system design, technical process safety, and process safety management implementation. Rahul has successfully led major projects in oil and gas, petrochemical, and chemical industries, including relief system gap assessments, HAZOP studies, quantitative risk assessments, and implementing process safety standards.

Mr. Pramod Mekhya
Mr. Pramodbhai Mekhya is a seasoned Chemical Engineer and Process Safety Specialist with over 19 years of industrial experience spanning process development, process safety, scale-up, and advanced calorimetry techniques in the pharmaceutical and chemical industries.
He has extensive hands-on expertise in thermal hazard assessment, reaction calorimetry, adiabatic calorimetry, and process scale-up, supporting both R&D laboratories and manufacturing plants to design safer and more efficient chemical processes. He brings a rare combination of industrial manufacturing experience and advanced safety instrumentation expertise, enabling participants to gain practical insights into reaction hazard evaluation, calorimetry data interpretation, and safe process scale-up strategies.

PSCI Chair Rob Williams, Senior Director of Sustainable Procurement at AstraZeneca, will be speaking at ethica26 – the Human Rights in Supply Chains Leadership Summit, taking place in London on 17 March 2026.

Rob will share practical insight into how procurement leaders can move beyond policies and audits to embed human rights into everyday sourcing decisions, strengthening accountability, resilience, and supplier partnerships across global supply chains.

ethica26 brings together senior leaders from procurement, sustainability, legal, and investment functions to explore what effective, credible action on forced labour and human rights looks like in practice.

PSCI Members are encouraged to join the conversation and connect with peers facing similar challenges across complex supply chains.

PSCI Member 20% discount available: PSCI26

Learn more here: ethica26: Human Rights in Supply Chains Leadership Summit, London

The Energize program aims to increase access to renewable electricity for suppliers in the pharmaceutical industry. The program is growing and now has 26 global pharmaceutical companies working to support their suppliers to decarbonize and mitigate the overall environmental impact of the industry. Join Schneider Electric, Energize program manager, to learn more about the program and benefits of participating.

Agenda
What is Energize?
Why is Energize important?
Program Education
Renewable Electricity Procurement Support
Program Benefits
What to expect when you join the program and next steps

Choose your session
Wednesday 11 February
Thursday 12 February

About Energize
The Energize program is a supply chain renewables initiative designed and delivered by Schneider Electric Sustainability Business and endorsed by the PSCI.

Current Energize sponsors: Almirall, Amgen, Astellas, AstraZeneca, Bayer, Boehringer Ingelheim, Bristol Myers Squibb, Charles River Laboratories, Chiesi Group, GSK, Haleon, Johnson & Johnson, Kenvue, Merck (known as MSD outside the United States and Canada), Merck KGaA, Darmstadt, Germany, Novartis, Novo Nordisk, Pfizer, Roche, Sandoz, Sanofi, Schott, Takeda, Teva, UHG, and UCB.

この講演の言語は日本語です
This presentation will be delivered in Japanese

テーマ
AMRの脅威と製薬企業の責任：製薬業界をあげた活動とSHIONOGIグループの取り組み

PSCIアカウントに登録／ログイン後、申し込みができます。申し込みは12月17日午後5時までとなります。参加ガイドメールは12月18日に送信されます。

講演者
徐 文嘉, アソシエイトディレクター（MSD グローバル安全・環境）| PSCI 能力委員会 共同リード
Wenjia は MSD のグローバル安全・環境部門に所属し、API／中間体サプライヤー、製剤メーカー、そして買収・統合プロジェクトに対する EHS のデューデリジェンスおよび評価を担当しています。BASF、ロシュ、J&J での勤務経験を含め、Wenjia は化学・製薬業界で 20 年にわたり EHS の専門家として従事してきました。特に過去 8 年間では、複数の PSCI 監査および能力強化活動に参画しており、PSCIの原則について深い知見を有しています。

大橋 興三，コーポレートガバナンス部 総務EHS担当者
SHIONOGIグループにおけるEHS（環境・健康・安全）統括組織での3年間の経験を有し、AMR（薬剤耐性）対策における責任ある製造の推進を担当。AMR Industry AllianceのManufacturing Working Groupメンバーとして、国際的な枠組みにおける製造環境改善にも取り組んでいる。以前は18年間にわたり臨床開発部門にて新薬の開発業務に従事し、抗菌薬の開発にも携わる。

概略
薬剤耐性菌（AMR：Antimicrobial Resistance）は、世界の医療に深刻な影響を及ぼす重要な課題です。本Webinarでは、AMRの基本的な知識をわかりやすく解説し、製薬業界がどのように対応すべきかをご紹介します。
具体的には、AMR Industry Allianceによる抗菌薬製造基準（Antibiotic Manufacturing Standard）や、新たな認証制度を取り上げ、業界全体で進められている取り組みを理解します。
さらに、SHIONOGIグループが推進する具体的な施策についてもご紹介し、持続可能な医療の実現に向けた道筋を考えます。
AMR問題の本質と解決へのアプローチを学ぶ貴重な機会です。ぜひご参加ください。

Topic
PSCI Introduction, the Threat of AMR and Pharmaceutical Responsibility: Industry-Wide Initiatives in the Pharmaceutical Sector and SHIONOGI Group’s Commitment

Presenter
Wenjia Xu, Associate Director, Global Safety and Environment, MSD| PSCI capability committee co-lead
Wenjia is a part of MSD Global safety and environment, responsible for performing EHS due diligence and assessment for API/Intermediate suppliers, formulation manufactures and acquisition & integration projects. Including previously being with BASF, Roche, and J&J, Wenjia has been working as EHS professional in chemical and pharmaceutical industries for 20 years, . Among that, in the last 8 years, Wenjia was engaged in several PSCI audits and capability activities, which makes him have strong insights on PSCI principles.

Kozo Ohashi, EHS Management Group Member, Corporate Governance Department, Shionogi
Kozo Ohashi has three years of experience in the Environmental, Health, and Safety (EHS) management division of the SHIONOGI Group, where he led initiatives for responsible manufacturing in the context of antimicrobial resistance (AMR). He is also a member of the Manufacturing Working Group of the AMR Industry Alliance, contributing to global efforts to improve manufacturing practices in the fight against AMR. Prior to this role, he spent 18 years in clinical development, contributing to the research and development of new drugs, including antibiotics.

Introduction
Antimicrobial Resistance (AMR) is a critical global challenge that poses serious threats to healthcare systems worldwide. This webinar will provide a clear overview of the fundamentals of AMR and outline how the pharmaceutical industry should respond to this pressing issue.
It will introduce the Antibiotic Manufacturing Standard developed by the AMR Industry Alliance and highlight emerging certification schemes designed to ensure responsible practices across the industry. In addition, key initiatives led by the SHIONOGI Group will be presented, illustrating the path toward sustainable healthcare.
This session offers a valuable opportunity to deepen your understanding of AMR and explore practical approaches to addressing this global concern. We look forward to your participation.

About: As pharmaceutical supply chains continue to expand and grow in complexity, creating safe, resilient, and learning-driven operations has never been more important. Human and Organizational Performance (HOP) offers a framework for understanding how people actually work within complex systems - and how organisations can respond to incidents and failures in ways that strengthen, rather than weaken, safety performance.

In this PSCI webinar, our speakers will demystify HOP through real stories, practical examples, and behavioural science insights. Participants will explore what a HOP response to failure looks like in practice, how it differs from other safety approaches, and how adopting HOP principles can enhance both operational reliability and worker well-being across the supply chain.

Speakers:

• Andrea (Andy) Baker
  Andrea Baker is a leading practitioner of Human and Organizational Performance (HOP), with experience implementing HOP principles across global manufacturing, assembly, and distribution environments. She has supported more than 90 companies across 9 industries and 16 countries in embedding operational learning. Andrea co-authored Bob’s Guide to Operational Learning and co-hosts A HOP Podcast.
• Matt Florio
  Matt Florio brings a background in education, training, and executive leadership to the HOP space, helping organisations understand and apply HOP concepts beyond traditional safety contexts. He has partnered with 34 companies across 10 industries and is a co-host of A HOP Podcast.

PSCI invites our approved audit firms and interested external firms to participate in the next audit firm quarterly virtual meeting on December 11th between 1-2 pm CET. The meeting is a great chance to connect with the Audit Committee Leads and stay informed about the latest developments in the audit program.

Agenda

• Updates on the use of data sharing agreement (DSA) of PSCI audits
• Incident escalation process
• Link 2.0 updates
• Auditor Q&A