LOG IN

Members and suppliers: Join our online community

Access our full library of resources, register for events and webinars and share audits and other assessments

Our resource library is made available freely to all in order to advance responsible supply chain practices. Here you will find information and guidance on responsible supply chain issues and the way that PSCI works. If you have any suggestions for improvements or additions to our resources please contact us.

Search & Filter

Clear Filters
1 2 all

Guidance for calculating dilution factors considering mixing zones

Document
28 Sep 2021

The following document provides guidance on potential techniques, methodologies, and available data sources for the calculation of dilution factors. The correct approach to follow is dependent on specific aspects of the risk assessment to be conducted. The PSCI does not advocate a single correct approach or data source, but aims to provide information to help risk assessors design assessments suitable for their requirements.

The contents of this document has been kindly shared by the IAI PiE Task Force.

  • Pharmaceuticals In The Environment
  • Anti-Microbial Resistance

Sampling and Analysis of Pharmaceutical Industry Wastewater for Active Pharmaceutical Ingredients

Document
28 Sep 2021

The following document provides guidance on potential techniques, methodologies, and available data sources for sampling and analysis of pharmaceutical industry wastewater. The correct approach to follow is dependent on specific aspects of the risk assessment to be conducted. The PSCI does not advocate a single correct approach or data source, but aims to provide information to help risk assessors design assessments suitable for their requirements.

The contents of this document has been kindly shared by the IAI PiE Task Force.

  • Pharmaceuticals In The Environment
  • Anti-Microbial Resistance

PSCI Supplier Conference 2021 China Session 1: Practices to achieve carbon reduction targets - Slides

Slides
9 Sep 2021

This presentation was delivered by
碳减排实践与CSR报告 由下列嘉宾分享:

  • Joyce Xiong, Consultant Director, ERM | 熊昀青, 顾问总监, 伊尔姆环境资源管理咨询公司

This session was facilitated by Maggie Zhang, Senior Partner at Carnstone.
本环节由凯嵘管理咨询高级合伙人张缤莉主持。

The slides are available for download below.
会议PPT请在下方点击“DOWNLOAD”下载。

PSCI features in CPhI Podcast on PiE

PSCI features in CPhI Podcast on PiE

Link
13 Apr 2021

More great publicity for the PSCI with thanks to Dan Caldwell (Johnson & Johnson) and Steve Brooks (AMR Alliance) who recently recorded this CPhI podcast on pharmaceuticals in the environment (PiE) and anti-microbial resistance (AMR) and what the industry is doing to help address the challenge.

The PSCI has published a PEC:PNEC calculator tool for manufacturers to use to calculate how to meet safe levels of discharge for active pharmaceutical ingredients (APIs) from their sites.

Image credit: CPhI

  • Pharmaceuticals In The Environment
  • Anti-Microbial Resistance

PSCI ENVIRONMENTAL SURVEY FOR SUPPLIERS - GUIDANCE FOR SUPPLIERS

Document
12 Apr 2021

This document is a step by step guidance on using the PSCI Environmental survey for suppliers on the PSCI platform. If you have any further questions, please do not hesitate to contact us.

  • Environment
  • Waste Management
  • Water Use & Management
  • Energy Use & Carbon Footprint
  • Sustainability Data

CELEBRATING WORLD HEALTH DAY - PSCI POSITION STATEMENT ON PIE & AMR

Publications & Newsletters
6 Apr 2021

At the PSCI, we’re committed to doing everything in our power to limit that the spread and growth of two emerging threats – Pharmaceuticals in the Environment (PiE) and Anti-microbial Resistance (AMR). That’s why for World Health Day, we’re excited today to launch our new Position Statement, which provides a clear explanation of the critical role we play in helping our supplier partners improve their manufacturing practices. The statement has been written to highlight the relevance of the PiE issue along the supply chain, to articulate the PSCI's position on this high profile topic, and to help answer stakeholder inquiries. It includes an overview of all PSCI resources on PiE and AMR-related issues.

  • Environment
  • Pharmaceuticals In The Environment
  • Anti-Microbial Resistance

2020 PSCI AUDITOR TRAINING (VIRTUAL) - SESSION 2 - RECORDING AND SLIDES

Training
1 Feb 2021

The second session of the 2020 PSCI Auditor Training (Virtual) took place virtually on 25 November and covered below presentations.

  • Environmental protection
    Manjit Singh, Associate Director- Corporate Sustainability, Centrient Pharmaceuticals
  • Stormwater management and Zero Liquid Discharge key points
    Daniel Rehm, HSE Advisor, External Manufacturing EMEA & API, Elanco
  • Introduction to PiE and AMR
    Dr Paul Barnett, Director, Environment Health & Safety, GlaxoSmithKline
  • Assessing Antibiotic Manufacturing Sites Capability in Controlling their Antibiotic Emissions
    Jonathan Stanway, Downstream & Pilot Plant Manager, Biotechnology & Environmental Shared Service, Pharma Supply Chain, GlaxoSmithKline

This session was facilitated by Maggie Zhang, Partner Manager at Carnstone.

The recording of the session is available here. Chinese users can download the recording here (password: PSCI).
Slides are available for download below.

  • Environment
  • Audit Programme

PSCI Supplier Conference 2020 China Session 2: Case studies on WWT technology - Recording and slides

Training
22 Oct 2020

This presentation on Case studies on WWT technology was delivered by:
此演讲由下列嘉宾分享PiE:废水处理技术案例

  • Ken Sun, EHS&S Lead -Third Party, GSK | 孙大勇,第三方EHS&S主管,葛兰素史克
  • Wenjun Wang, Senior EHS Manager, Pfizer Global Environment, Health and Safety | 王文君, 高级EHS经理,辉瑞

This session was facilitated by Maggie Zhang, Partner Manager at Carnstone.
本环节由凯嵘管理咨询合伙人经理张缤莉主持。

The recording is available here (code:PSCI). The slides are available for download below.
会议视频请点击此 链接 获取 (提取码 PSCI)。会议PPT请在下方点击“DOWNLOAD”下载。

  • Environment
  • Pharmaceuticals In The Environment
  • Anti-Microbial Resistance

PSCI Supplier Conference 2020 China Session 2: Whole effluent toxicity (WET) testing methods and application - Recording and slides

Document
22 Oct 2020

This presentation on EWhole effluent toxicity (WET) testing methods and application was delivered by:
此演讲由下列嘉宾分享全废水毒性测试方法与应用:

  • Xiaoqian Chen, Senior Engineer, Bioassay and Safety Assessment Laboratory, Shanghai | 陈晓倩, 高级工程师, 上海市检测中心 生物与安全检测实验室

This session was facilitated by Maggie Zhang, Partner Manager at Carnstone.
本环节由凯嵘管理咨询合伙人经理张缤莉主持。

The recording is available here (code:PSCI). The slides are available for download below.
会议视频请点击此 链接 获取 (提取码 PSCI)。会议PPT请在下方点击“DOWNLOAD”下载。

  • Environment
  • Pharmaceuticals In The Environment
  • Anti-Microbial Resistance

PSCI Supplier Conference 2020 China Session 2: How to do a mass balance calculation - Recording and slides

Training
22 Oct 2020

This presentation on How to do a mass balance calculation was delivered by:
此演讲由下列嘉宾分享生态环境中药物活性成分的总量平衡计算 :

  • Ken Sun, EHS&S Lead -Third Party, GSK | 孙大勇,第三方EHS&S主管,葛兰素史克
  • Wenjun Wang, Senior EHS Manager, Pfizer Global Environment, Health and Safety | 王文君, 高级EHS经理,辉瑞

This session was facilitated by Maggie Zhang, Partner Manager at Carnstone.
本环节由凯嵘管理咨询合伙人经理张缤莉主持。

The recording is available here (code:PSCI). The slides are available for download below.
会议视频请点击此 链接 获取 (提取码 PSCI)。会议PPT请在下方点击“DOWNLOAD”下载。

PSCI Supplier Conference 2020 China Session 2: Environmental hazards of drugs and case analysis - Recording and slides

Training
22 Oct 2020

This presentation on Environmental hazards of drugs and case analysis was delivered by:
此演讲由下列嘉宾分享药物的环境危害与案例分析 :

  • Min Liu, Head of Tech, Bioassay and Safety Assessment Laboratory, Shanghai | 刘敏, 技术总监, 上海市检测中心 生物与安全检测实验室

This session was facilitated by Maggie Zhang, Partner Manager at Carnstone.
本环节由凯嵘管理咨询合伙人经理张缤莉主持。

The recording is available here (code:PSCI). The slides are available for download below.
会议视频请点击此 链接 获取 (提取码 PSCI)。会议PPT请在下方点击“DOWNLOAD”下载。

PSCI Supplier Conference 2020 China Session 2: Sustainable packaging - Recording and slides

Training
22 Oct 2020

This presentation on sustainable packaging was delivered by:
此演讲由下列嘉宾分享可持续包装:

  • Zelia Kranich, Sustainable Sourcing Associate Director, Merck & Co., Inc. | Zelia Kranich, 可持续副总监, 默沙东
  • Victor Bell, US Managing Director, Lorax EPI | Victor Bell, 美国常务董事, Lorax EPI
  • Jacqueline Hollands, Global Manager, Customer Sustainability Solutions, MilliporeSigma | Jacqueline Hollands, 客户可持续发展解决方案全球经理,密理博西格玛

This session was facilitated by Maggie Zhang, Partner Manager at Carnstone.
本环节由凯嵘管理咨询合伙人经理张缤莉主持。

The recording is available here (code:PSCI). The slides are available for download below.
会议视频请点击此 链接 获取 (提取码 PSCI)。会议PPT请在下方点击“DOWNLOAD”下载。

PSCI SUPPLIER CONFERENCE 2020 CHINA SESSION 2: Taking climate action - RECORDING AND SLIDES

Training
22 Oct 2020

This presentation on taking climate action was delivered by:
此演讲由下列嘉宾分享应对环境变化主题:

  • Maggie Zhang, Partner Manager, Carnstone | 张缤莉, 合伙人经理,凯嵘管理咨询

This session was facilitated by Maggie Zhang, Partner Manager at Carnstone.
本环节由凯嵘管理咨询合伙人经理张缤莉主持。

The recording is available here (code:PSCI). The slides are available for download below.
会议视频请点击此 链接 获取 (提取码 PSCI)。会议PPT请在下方点击“DOWNLOAD”下载。

PSCI SUPPLIER CONFERENCE 2020 CHINA SESSION 2: PSCI Environment sub-team Overview - RECORDING AND SLIDES

Training
22 Oct 2020

This is the opening address of the PSCI Virtual China Supplier Conference 2020, delivered by:
此会议内容为PSCI 环境工作小组简介,我们很开心能够邀请两位嘉宾出席:

  • Rikke Christensen, Head of Sustainable Procurement, LEO Pharma | Rikke Christensen, 可持续采购负责人, 利奥制药
  • Zelia Kranich, Sustainable Sourcing Associate Director, Merck & Co., Inc. | Zelia Kranich, 可持续副总监, 默沙东(在美国和加拿大称为默克公司)

This session was facilitated by Maggie Zhang, Partner Manager at Carnstone.
本环节由凯嵘管理咨询合伙人经理张缤莉主持。

The recording is available here (code:PSCI). The slides are available for download below.
会议视频请点击此 链接 获取 (提取码 PSCI)。会议PPT请在下方点击“DOWNLOAD”下载。

PSCI China Supplier Conference 2020 - Session 2 - Full recording and slides | 2020年PSCI 供应商会议(中国) - 第二场 - 完整视频和PPT

Training
22 Oct 2020

The second session of the 2020 PSCI China supplier conferences took place virtually on 24 September and covered Environment, Pharmaceuticals in the Environment/AMR.

The full recording of the session is available here (code:PSCI). Slides are available for download below.

Recordings and slides of individual presentations are also available as individual resources - please click on the relevant links below:

2020 PSCI线上供应商会议(中国)第二场在9月24日举行,会议内容包括环境,环境中药物残留及抗微生物药物耐药性。

本次会议的完整视频请点击链接 获取 (提取码 PSCI) 获取会议视频。会议PPT请在下方点击“DOWNLOAD”下载。

每个环节单独的视频和PPT也已上传至本网站。请点击下列相关链接获取:

  • Environment
  • Pharmaceuticals In The Environment
  • Anti-Microbial Resistance

PSCI Supplier Conference 2020 China Session 1: Updates on China REACH - Recording and Slides

Training
9 Oct 2020

This presentation sharing the key points from China’s “Measures for Environmental Management Registration of New Chemical Substances” was delivered by:
此演讲由下列嘉宾介绍中国新化学物质环境管理办法的最新进展:

  • Lingzhen Dong, Asia Pacific Region -Product Stewardship Director, Johnson & Johnson | 董玲珍,亚太区EHS&S产品监管总监,强生(中国)

This session was facilitated by Maggie Zhang, Partner Manager at Carnstone.
本环节由凯嵘管理咨询合伙人经理张缤莉主持。

The recording is available here (code: PSCI). The slides are available for download below.
会议视频请点击此链接 获取 (提取码:PSCI) 获取会议视频。会议PPT请在下方点击“DOWNLOAD”下载。

  • Management Systems
  • Chemical Registrations
SCOPE 3 GREENHOUSE GAS EMISSIONS CALCULATION: GUIDANCE FOR THE PHARMACEUTICAL INDUSTRY

SCOPE 3 GREENHOUSE GAS EMISSIONS CALCULATION: GUIDANCE FOR THE PHARMACEUTICAL INDUSTRY

Document
5 Oct 2020

The primary focus of this document is to provide a consistent guidance for pharmaceutical companies to calculate GHG emissions in their upstream and downstream value chains. It provides methodologies consistent with recommendations from the GHG Protocol for calculating emissions which are tailored for each different category.

This document was developed by the Pharmaceutical Environment Group (PEG) and its participating companies, who have kindly shared it with the PSCI for diffusion.

  • Environment
  • Energy Use & Carbon Footprint

PSCI supplier Conference 2020 India Session 2: Indian Case Study on Controlling API Releases - Recording and slides

Training
2 Oct 2020

This presentation on Indian Case Study on Controlling API Releases Including Wastewater Treatment/Analysis was delivered by:

  • Jon Peers, Director of Environment, Teva

This session was facilitated by Annabel Buchan, Partner Manager at Carnstone.

The recording is available here. The slides are available for download below.

  • Environment
  • Pharmaceuticals In The Environment
  • Anti-Microbial Resistance

PSCI supplier Conference 2020 India Session 2: Introduction to sampling and analysing APIs in wastewater - Recording and slides

Training
2 Oct 2020

This introduction to sampling and analysing APIs in wastewater was delivered by:

  • Jon Stanway, Biotechnology & Environmental Downstream Manager, GSK

This session was facilitated by Annabel Buchan, Partner Manager at Carnstone.

The recording is available here. The slides are available for download below.

  • Environment
  • Pharmaceuticals In The Environment
  • Anti-Microbial Resistance

PSCI supplier Conference 2020 India Session 2: Draft Indian Wastewater Standards - Recording and slides

Training
2 Oct 2020

This presentation on Draft Indian Wastewater Standards - Current Status and Possible Ramifications for Indian companies was delivered by:

  • Mugundan Ramachandran, Senior Consultant, ERM India Private Limited
  • Shivananda Shetty, Partner & Commercial Director, ERM India Private Limited

This session was facilitated by Annabel Buchan, Partner Manager at Carnstone.

The recording is available here. The slides are available for download below.

  • Environment
  • Pharmaceuticals In The Environment
  • Anti-Microbial Resistance

PSCI supplier Conference 2020 India Session 2: Sustainable packaging - Recording and slides

Training
2 Oct 2020

This presentation on Sustainable Packaging was delivered by:

  • Jacqueline Hollands, Global Manager, Customer Sustainability Solutions, MilliporeSigma
  • Victor Bell, US Managing Director, Lorax EPI
  • Zelia Kranich, Sustainable Sourcing Associate Director, Merck & Co., and PSCI Environment Sub-Team Co-Lead

This session was facilitated by Annabel Buchan, Partner Manager at Carnstone.

The recording is available here. The slides are available for download below.

PSCI supplier Conference 2020 India Session 2: Taking climate action - Recording and slides

Training
2 Oct 2020

This presentation on Taking Climate Action was delivered by:

  • Glynn Roberts, Director and Senior Partner, Carnstone

This session was facilitated by Annabel Buchan, Partner Manager at Carnstone.

The recording is available here. The slides are available for download below.

PSCI supplier Conference 2020 India Session 2: PSCI Environment Sub-Team Overview - Recording and slides

Training
2 Oct 2020

This PSCI Environment Sub-Team Overview was delivered by:

  • Rikke Christensen, Head of Sustainable Procurement, LEO Pharma, and PSCI Environment Sub-Team Co-Lead
  • Zelia Kranich, Sustainable Sourcing Associate Director, Merck & Co., and PSCI Environment Sub-Team Co-Lead

This session was facilitated by Annabel Buchan, Partner Manager at Carnstone.

The recording is available here. The slides are available for download below.

PSCI India Supplier Conference 2020 - Session 2 - Full recording and slides

Training
2 Oct 2020

The second session of the 2020 PSCI India supplier conferences took place virtually on 24 September and covered Environment and Pharmaceuticals in the Environment/AMR.

The full recording of the session is available here. Slides are available for download below.

Recordings and slides of individual presentations are also available as individual resources - please click on the relevant links below:

PSCI supplier Conference 2020 India Session 1: India Chemical Management & Safety Rules (ICMSR) - Recording and slides

Training
2 Oct 2020

This presentation on India Chemical Management & Safety Rules (ICMSR) was delivered by:

  • Jayachandran Nair, CEO, Global Product Compliance (GPC) India

This session was facilitated by Simon Hodgson, Managing Partner at Carnstone.

The recording is available here. The slides are available for download below.

  • Health & Safety
  • Management Systems
  • Chemical Registrations

PiE/AMR Webinar (Wastewater treatment technologies) - Recording and slides

Webinar
14 Sep 2020

The webinar explored best practice wastewater treatment methods for managing the release of APIs into the environment from pharmaceutical manufacturing sites. It was delivered by renowned experts and featured case studies on novel treatment technologies.

We were delighted to be joined by the following speakers:

  • Jeffrey Brenchley from Merck (MSD) (Senior Specialist, Global Safety & Environment), speaking about vacuum evaporation
  • Birgit Mertens from Johnson & Johnson (Senior Principal Environment Worldwide EHS&S), speaking about ozone as pretreatment
  • Jonathan Rhone from Axine Water Technologies Inc. (President and CEO), speaking about electrochemical oxidation

Participants are invited to share feedback about this webinar here.

The recording is available here. (Please refresh the page if you cannot play the video.)

The slides used during the webinar are available to download below.

Please also note that registration for the second session of our supplier conferences is open until 17 September. Topics covered will include climate change (GHG) & sustainable packaging ; sampling and analysing APIs in wastewater with case studies ; a case study on Controlling API Releases; environmental hazards of drugs and case analysis ; and mass balance calculations. To register, please click here for the China session and here for the India session.

Finally, we want your views! We're encouraging all suppliers to take this short survey to help the PSCI understand the impact it has on suppliers.

  • Spills & Releases
  • Waste Management
  • Pharmaceuticals In The Environment
  • Anti-Microbial Resistance

Full PSCI SAQ & Audit Report Template (WORD VERSION)

Document
19 Apr 2020

MS Word version
PSCI Self Assessment Questionnaire and Audit Report Template for Core Suppliers, External Manufacturers, Component and Material Suppliers

More Info…
Select your preferred language from the options below
  • Ethics
  • Human Rights & Labor
  • Health & Safety
  • Environment
  • Management Systems
  • Audit Programme

PSCI Position Statement on PiE & AMR

Publications & Newsletters
27 Mar 2020

On behalf of the Board and Communications Committee and with thanks to the Pharmaceuticals in the Environment (PiE)/ Anti-Microbial Resistance (AMR) sub-team for their expert input, we are sharing the recently adopted PSCI Position Statement on PiE & AMR. It has been written to highlight the relevance of the PiE issue along the supply chain, to articulate PSCI's position on this high profile topic, and to help answer stakeholder inquiries. It includes an overview of all PSCI resources on PiE and AMR-related issues.

  • Pharmaceuticals In The Environment
  • Anti-Microbial Resistance

2019 PIE/AMR Deep Dive Seminar - Slide deck

Slides
16 Jan 2020

The compiled slide deck from the PIE/AMR Deep Dive training seminar held on 17th September 2019 in Hyderabad, India.

  • Pharmaceuticals In The Environment
  • Anti-Microbial Resistance
The PSCI Principles

The PSCI Principles

Organisational Information
26 Nov 2019

The 2019 revision of the PSCI Principles (PSCI Principles v2.0) was approved by the membership on Tuesday 12th November, 2019, at the Annual General Meeting in Cambridge, Massachusetts, and became effective on 1st January 2020.

The PSCI Principles for Responsible Supply Chain Management set the standard for human rights, ethics, labor, health and safety, environment and related management systems.The Principles may be voluntarily supported by any business in the pharmaceutical industry.

The Principles now include a specific reference to human rights and the UN Guiding Principles on Business and Human Rights, an enhanced ethics section, and new clauses on resource efficiency and sustainable sourcing.

Select your preferred language from the options below
  • Ethics
  • Human Rights & Labor
  • Health & Safety
  • Environment
  • Management Systems

Webinar slide deck: Antimicrobial Resistance

Slides
23 Jul 2019

This webinar initially aired on 18th July 2019

In this webinar we will be looking at the impact of pharmaceutical manufacturing on antimicrobial resistance, as well as demonstrating PSCI's PEC:PNEC calculator tool.

Our speakers will be covering the issues associated with antimicrobial drugs in wastewater, targets for environmental risk assessment of antimicrobial drugs, and how to assess the risk of antimicrobial drugs in wastewater.

We are delighted to be joined by the following speakers:

  • Daniel Caldwell, Global Director, Environmental and Occupational Toxicology at Johnson & Johnson;
  • Neil Parke, Global HSE Consultant at Lilly.

Finally, we want your views! We're encouraging all suppliers to take this short survey to help the PSCI understand the impact it has on suppliers.

  • Pharmaceuticals In The Environment
  • Anti-Microbial Resistance

Webinar recording: Antimicrobial Resistance

Webinar Video Link
23 Jul 2019

This webinar initially aired on 18th July 2019

In this webinar we will be looking at the impact of pharmaceutical manufacturing on antimicrobial resistance, as well as demonstrating PSCI's PEC:PNEC calculator tool.

Our speakers will be covering the issues associated with antimicrobial drugs in wastewater, targets for environmental risk assessment of antimicrobial drugs, and how to assess the risk of antimicrobial drugs in wastewater.

We are delighted to be joined by the following speakers:

  • Daniel Caldwell, Global Director, Environmental and Occupational Toxicology at Johnson & Johnson;
  • Neil Parke, Global HSE Consultant at Lilly.
  • Pharmaceuticals In The Environment
  • Anti-Microbial Resistance

Consolidated PEC:PNEC Calculator Tool for assessing API discharges

Document
11 Jul 2019

This Excel spreadsheet tool provides instructions and guidance on how to assist pharmaceutical manufacturers in calculating how to meet predicted no effect concentration values (PNECs) for active pharmaceutical ingredients (APIs) discharged in wastewater from manufacturing operations.

  • Environment
  • Spills & Releases
  • Waste Management
  • Water Use & Management
  • Pharmaceuticals In The Environment
  • Anti-Microbial Resistance

Abbreviated PSCI SAQ & Audit Report Template (WORD VERSION)

Document
7 Feb 2019

WORD VERSION
Abbreviated PSCI Self Assessment Questionnaire & Audit Report Template for Service Providers & General Manufacturers

Version 5, February 2019
Version 6, remote audit options added, October 2020

Full version template for Core Suppliers, External Manufacturers, Component and Material Suppliers are also available and come in multiple languages: Word version, Excel version.

  • Ethics
  • Human Rights & Labor
  • Health & Safety
  • Environment
  • Management Systems
  • Audit Programme

2018 China Supplier Conference Presentation Pack Day 1

Document
21 Sep 2018

Day 1 presentation pack from the 2018 Supplier Conference in Shanghai, China.

  • Ethics
  • Human Rights & Labor
  • Health & Safety
  • Environment
  • Management Systems
  • Pharmaceuticals In The Environment
  • Anti-Microbial Resistance

Webinar slide deck - managing APIs in manufacturing effluent Part 4 - 10th July 2018

Slides
11 Jul 2018

This is the slide deck from the PSCI sponsored webinar on how to manage APIs in manufacturing effluent (Part 4) which took place on 10th July 2018.

The webinar gave a brief refresher on Pharmaceuticals in the Environment (PiE), Anti-Microbial Resistance (AMR) and Predicted No-Effect Concentration (PNEC) first principles, and introduced a PSCI resource page where PNECs can be found. It also included step-by-step guidance on how to locate PNECs and use them.

  • Environment
  • Pharmaceuticals In The Environment
  • Anti-Microbial Resistance

Webinar recording - managing APIs in manufacturing effluent Part 4 - 10th July 2018

Webinar Video Link
11 Jul 2018

This is recording of the PSCI sponsored webinar on how to manage APIs in manufacturing effluent (Part 4) which took place on 10th July 2018.

The webinar gave a brief refresher on Pharmaceuticals in the Environment (PiE), Anti-Microbial Resistance (AMR) and Predicted No-Effect Concentration (PNEC) first principles, and introduced a PSCI resource page where PNECs can be found. It also included step-by-step guidance on how to locate PNECs and use them.

  • Environment
  • Pharmaceuticals In The Environment
  • Anti-Microbial Resistance

Predicted-No-Effect-Concentration (PNEC) resource links

Link
11 Jun 2018

The following are useful resources for obtaining PNEC values.

  1. AMR Industry Alliance Antibiotic Discharge Targets - List of Predicted No-Effect Concentrations (PNECs).
    The PNEC table contains two values, PNEC‐Environment (PNEC‐ENV) values based on eco-toxicology and PNEC‐Minimum Inhibitory Concentration (PNEC‐MIC) values intended to be protective of resistance promotion.
    The AMR Industry Alliance recommendation is that companies target the lower of these two values (when available) for assessing manufacturing site discharges under a risk‐based framework.
  2. Temple WET Center PNEC database where you will find PNEC values for APIs other than antibiotics.
  • Pharmaceuticals In The Environment
  • Anti-Microbial Resistance

Webinar slide deck - managing APIs in manufacturing effluent Part 3 - 25th October 2016

Slides
26 Oct 2016

This is the slide deck for the PSCI sponsored webinar on how to manage APIs in manufacturing effluent (Part 3) which took place on 25th October 2016. The webinar looked at advanced technologies to reduce API loss with guest speakers from the Temple University WET Centre and AECOM.

  • Environment
  • Pharmaceuticals In The Environment

Webinar recording - managing APIs in manufacturing effluent Part 2 - 15th June 2016

Webinar Video Link
20 Jun 2016

This is recording of the PSCI sponsored webinar on how to manage APIs in manufacturing effluent (Part 2) which took place on 15th June 2016. The webinar provided step-by-step guidance on this ‘spotlight’ issue for our industry and covered the following topics:

  • estimating actual API losses from the manufacturing process (PEC)
  • establishing the acceptable discharge concentration (PNEC)
  • making low capital investment housekeeping steps to reduce the loss of APIs
  • Environment
  • Pharmaceuticals In The Environment

Webinar slide deck - managing APIs in manufacturing effluent Part 2 - 15th June 2016

Slides
20 Jun 2016

This is the slide deck for the PSCI sponsored webinar on how to manage APIs in manufacturing effluent (Part 2) which took place on 15th June 2016. The webinar provided step-by-step guidance on this ‘spotlight’ issue for our industry and covered the following topics:

  • estimating actual API losses from the manufacturing process (PEC)
  • establishing the acceptable discharge concentration (PNEC)
  • making low capital investment housekeeping steps to reduce the loss of APIs
  • Environment
  • Pharmaceuticals In The Environment

Webinar slide deck - managing APIs in manufacturing effluent Part 1 - 27th Jan 2016

Slides
3 Feb 2016

This is the slide deck for the PSCI sponsored webinar on how to manage APIs in manufacturing effluent which took place on 27th January 2016. The webinar provided step-by-step guidance on this ‘spotlight’ issue for our industry and covered the following topics:

  • Why is managing active pharmaceutical ingredients (API) in manufacturing effluent important?
  • What is the industry doing to improve public perceptions?
  • Understanding where you stand at the moment through the maturity ladder concept.
  • Establishing and calculating API discharge concentration called the Predicted-No-Effect-Concentration (PNEC).
  • Simple steps to reducing API process losses to waste water and what to do when the PNEC is exceeded.
  • How to advance your program to the next level.
  • Environment
  • Pharmaceuticals In The Environment

Webinar recording - managing APIs in manufacturing effluent Part 1- 27th Jan 2016

Webinar Video Link
3 Feb 2016

This is a recording of the PSCI sponsored webinar on how to manage APIs in manufacturing effluent which took place on 27th January 2016. The webinar provided step-by-step guidance on this ‘spotlight’ issue for our industry and covered the following topics:

  • Why is managing active pharmaceutical ingredients (API) in manufacturing effluent important?
  • What is the industry doing to improve public perceptions?
  • Understanding where you stand at the moment through the maturity ladder concept.
  • Establishing and calculating API discharge concentration called the Predicted-No-Effect-Concentration (PNEC).
  • Simple steps to reducing API process losses to waste water and what to do when the PNEC is exceeded.
  • How to advance your program to the next level.
  • Environment
  • Pharmaceuticals In The Environment

A risk based approach to managing APIs in manufacturing effluent

Document
20 Jan 2016

Abstract: This Caldwell et al. study describes guidance intended to assist pharmaceutical manufacturers in assessing, mitigating, and managing the potential environmental impacts of active pharmaceutical ingredients (APIs) in wastewater from manufacturing operations, including those from external suppliers.

  • Environment
  • Pharmaceuticals In The Environment

Find an EHS Consultant

Link
8 Jul 2015

The Premier Directory of Industrial Hygiene and Occupational and Environmental Health and Safety Consulting Professionals.

  • Health & Safety
  • Environment

Best Management Practices for Leak and Spill Control

Document
7 Jul 2015

Keeping a facility clean helps improve productivity and employee morale. In addition, it
presents a positive image to customers, stakeholders and the community. A clean facility can also help ensure greater compliance with environmental, health and safety regulations. Leaks and spills can happen anywhere – from the front office to the shipping dock; and beyond. These spills create waste and can lead to costly environmental fines - especially if the spill leaves the facility. Leaks and spills can also contribute to worker injuries, causing piles of medical bills, workman’s compensation claims and lost work time.

  • Environment
  • Spills & Releases

Water Position

Document
7 Jul 2015

An example is Bayer's “Science For A Better Life” where they promise innovative solutions to global economic, ecological and social challenges. The availability of fresh water is a growing concern around the world. Water is not only essential for life on earth but also for many industry sectors of the global economy and for us as a pharmaceutical and chemical company with energy and water intensive operations.

  • Environment
  • Water Use & Management

Climate Change Position

Document
7 Jul 2015

An example is Novo Nordisk's climate strategy, which is developed in accordance with the Greenhouse Gas Protocol. It includes all scope 1 and 2 emissions within operational control and scope 3 emissions that are significant in size or significant from a stakeholder perspective. Towards 2020 their focus is on reporting and reducing emissions from global production sites, company cars, product distribution and business travel.

http://www.novonordisk.com/about-novo-nordisk/novo-nordisk-in-brief/positions/climate-change.html

  • Environment
  • Energy Use & Carbon Footprint

Global Environmental Management Initiative (GEMI) Tools

Link
7 Jul 2015

A wide range of tools designed by GEMI to help companies improve the environment and provide business value.

  • Environment

Process Mass Intensity Calculation Tool

Link
7 Jul 2015

The PMI Calculator enables you to quickly determine the PMI value by accounting for the raw material inputs and bulk API outputs of a process.

Updated Version - http://www.acs.org/content/dam/acsorg/greenchemistry/industriainnovation/roundtable/Convergent-PMI-Tool.xlsx

  • Environment
1 2 all